Nos publications

Vous trouverez dans cette rubrique une sélection des articles que nous avons publiés récemment. Ces documents sont édités avec Acrobat Reader que vous pouvez télécharger gratuitement à l'adresse suivante :
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Dupic F, Fruchon S, Bensaid M, Borot N, Radosavljevic O, Loreal O, Brissot P, Gilfillan S, Bahram S, Coppin H, Roth MP. Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains. Gastroenterology 2002, 122 : 745-751.

Dupic F, Fruchon S, Bensaid M, Loreal O, Brissot P, Borot N, Roth MP, Coppin H. Duodenal mRNA expression of iron-related genes in response to iron loading and iron deficiency in four strains of mice. Gut 2002, 51 : 648-653.

Fruchon S, Bensaid M, Borot N, Roth MP, Coppin H. Use of denaturing HPLC and a heteroduplex generator to detect the HFE C282Y mutation associated with genetic hemochromatosis. Clin Chem 2003, 49 : 822-824.

Coppin H, Bensaid M, Fruchon S, Borot N, Blanche H, Roth MP. Longevity is not affected in carriers of the hemochromatosis gene C282Y mutation: a study of 492 centenarians. Br Med J 2003, 327 : 132-133.

Courselaud B, Troadec MB, Fruchon S, Ilyin G, Borot N, Leroyer P, Coppin H, Brissot P, Roth MP, Loreal O. Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice. Blood Cells Mol Dis 2004, 32: 283-289.

Bensaid M, Fruchon S, Mazères C, Bahram S, Roth MP, Coppin H. Multigenic control of hepatic iron loading in a murine model of hemochromatosis. Gastroenterology 2004, 126: 1400-1408.

Bensaid M, Fruchon S, Coppin H, Roth MP. Genes for gestational iron  loading ? Gastroenterology 2004, 127: 1861-1862.

Rohrlich PS, Fazilleau N, Ginhoux F, Firat H, Michel F, Cochet M, Laham N, Roth MP, Pascolo S, Nato F, Coppin H, Charneau P, Danos O, Acuto O, Ehrlich R, Kanellopoulos J, Lemonnier FA. Direct recognition by alpha beta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. PNAS 2005, 102: 12855-12860.

Coppin H, Darnaud V, Kautz L, Meynard D, Aubry M, Mosser J, Martinez M, Roth MP. Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regularory targets of Hfe and potential hemochromatosis modifiers. Genome Biol 2007, 8: R221.

Kautz L, Meynard D, Monnier A, Darnaud V, Bouvet R, Wang RH, Deng C, Vaulont S, Mosser J, Coppin H, Roth MP. Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver. Blood 2008, 112 : 1503-1509.

Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP. Lack of bone morphogenetic protein BMP6 induces massive iron overload. Nature Genetics 2009.